Cart
Checkout Secure

Coupon Code: 73215TODAY Copy Code

Free Shipping on Orders Over $50

Have a Question? Call Us

1-732-614-2031

7 Days a Week, 9am-6pm EST

  • Image of Chemix - Cortibloc - 732Supplements.com
  • Image of Chemix - Cortibloc - 732Supplements.com

Chemix - Cortibloc

Your Price:
$54.99
Quantity
 
Added to wishlist
Checkout Secure
Checkout Secure

Chemix - Cortibloc

Your Price:
$54.99
Currently out of stock
Order in the next  to get it by 

.. Visitor Right Now

Great reasons to buy from us:

  • Image of 100% Satisfaction Guaranteed
  • Image of Free shipping (when you spend over XXX)
  • Image of Free shipping (when you spend over XXX)

Chemix - Cortibloc

The science has proven that elevated cortisol levels cause stress on your adrenal system causing fatigue, rapid weight gain, stress and exhaustion. This is why The Guerrilla Chemist formulated his newest, highly potent product, Cortibloc™.

Cortibloc™ is a premium cortisol manager, blocker, and non stimulant fat burner. This product not only helps reduce cortisol levels but aids in relieving stress that makes you body want to retain unwanted fat.

Training hard is a key component in building a dense muscular physique but when the body encounters stress or does not get adequate rest the central nervous system (CNS) becomes fatigued. Over time your body will respond to stress and lack of rest by creating fat deposits in response to your hormones being under stress.

Cortibloc™ not only helps keep your cortisol levels down but it also helps burn unwanted fat and boosts your metabolism to new levels. Take on your stress with Cortibloc™ available now from Chemix!

  • Reduces Cortisol Levels
  • Aids At Fat Loss
  • Improves Adrenal Gland Function
  • Boosts Overall Energy
  • Creates Better Daily Mood

HOW DOES CORTIBLOC WORK?
CortiBloc™ is a one-of-a-kind natural cortisol inhibitor that can help with weight loss and regulate cortisol and blood glucose metabolism. The main ingredient in CortiBloc™ is emodin, an anthraquinone compound isolated mainly from the root and rhizome of polygonum cuspitatum, which acts as an 11βhydroxysteroid dehydrogenase 1(11β-HSD1) inhibitor. This enzyme, located in your liver and fat cells is responsible for the conversion of cortisone(the inactive glucocorticoid) into cortisol(the active form).

Glucocorticoids like cortisol can have deleterious effects on your body if levels get too high. Research has shown that elevated levels of glucocorticoids like cortisol can inhibit glucose uptake in skeletal muscle and can lead to fat gain, obesity, insulin resistance, hypertension, dyslipidemia and type-2 diabetes. Cortisol, which is produced in your adrenal glands in response to stress is good in small quantities and at the right time. However, long term elevated levels can have serious health implications, as mentioned earlier. Emodin can stop elevated cortisol levels right at the source. Emodin is a selective inhibitor of 11β-HSD1 only, not 11β-HSD2 which is found in your kidneys. Inhibiting this enzyme can cause major health effects such as sodium/potassium absorption/elimination, buildup of excess mineralocorticoids, interfere with aldosterone and affect kidney function.

Emodin inhibits 11β-HSD1 by blocking the enzyme site from sending a hydride from NADP to cortisone to produce cortisol. Studies show emodin inhibits the enzyme by up to 46% in adipose tissue(fat cells) which means your body is producing almost half of the cortisol it normally would. This can lead to fat loss, reduction in stress, decreased insulin resistance and increased insulin sensitivity. Emodin also reduced fasting blood glucose levels by 77% after taken orally for 7 days, as well as overall plasma insulin levels by 66% relative to the control. In another study, emodin was shown to reduce appetite and bodyweight in mice(13.9% reduction in bodyweight).

As you can see, emodin is a very powerful ingredient for inhibiting cortisol and insulin-induced weight gain. Unfortunately, the oral bioavailability is very low. In order to fix this issue, we added a large dose of piperine, commonly known as black pepper extract. In a study combining emodin with piperine showed a marked increase in bioavailability via inhibiting glucuronidation. This is the process where a glucose molecule is attached to emodin to make it more water soluble and easy to expel from the body. By stopping this process, the piperine allows emodin to maximally be absorbed and inhibit the formation of cortisol and help you meet and exceed your weight loss goals. This product can be taken by both men and women and works especially well for high-intensity athletes and fitness competitors.

______________________________________________________

Feng, Ying, et al. "Emodin, a natural product, selectively inhibits 11β‐hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet‐induced obese mice." British journal of pharmacology 161.1 (2010): 113- 126. Di, Xin, Xin Wang, and Youping Liu. "Effect of piperine on the bioavailability and pharmacokinetics of emodin in rats." Journal of pharmaceutical and biomedical analysis 115 (2015): 144-149. Wang, Yue-jing, et al. "Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice." Acta Pharmacologica Sinica 33.9 (2012): 1195.



Read The Studies On The Ingredients Below

https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1476-5381.2010.00826.x
https://www.nature.com/articles/aps201287#introduction


Shipping
Unfortunately we do not ship outside of the United States 
Delivery

Estimated between  and

Will usually ship within 1 business day.

   

Please allow 3-5 days for your order to arrive. All orders are processed and shipped within 24-48 hours unless otherwise noted.

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. Please note we can only accept unopened items for return or refund.

Here are more great reasons to buy from us:

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either.

Chemix - Cortibloc

The science has proven that elevated cortisol levels cause stress on your adrenal system causing fatigue, rapid weight gain, stress and exhaustion. This is why The Guerrilla Chemist formulated his newest, highly potent product, Cortibloc™.

Cortibloc™ is a premium cortisol manager, blocker, and non stimulant fat burner. This product not only helps reduce cortisol levels but aids in relieving stress that makes you body want to retain unwanted fat.

Training hard is a key component in building a dense muscular physique but when the body encounters stress or does not get adequate rest the central nervous system (CNS) becomes fatigued. Over time your body will respond to stress and lack of rest by creating fat deposits in response to your hormones being under stress.

Cortibloc™ not only helps keep your cortisol levels down but it also helps burn unwanted fat and boosts your metabolism to new levels. Take on your stress with Cortibloc™ available now from Chemix!

  • Reduces Cortisol Levels
  • Aids At Fat Loss
  • Improves Adrenal Gland Function
  • Boosts Overall Energy
  • Creates Better Daily Mood

HOW DOES CORTIBLOC WORK?
CortiBloc™ is a one-of-a-kind natural cortisol inhibitor that can help with weight loss and regulate cortisol and blood glucose metabolism. The main ingredient in CortiBloc™ is emodin, an anthraquinone compound isolated mainly from the root and rhizome of polygonum cuspitatum, which acts as an 11βhydroxysteroid dehydrogenase 1(11β-HSD1) inhibitor. This enzyme, located in your liver and fat cells is responsible for the conversion of cortisone(the inactive glucocorticoid) into cortisol(the active form).

Glucocorticoids like cortisol can have deleterious effects on your body if levels get too high. Research has shown that elevated levels of glucocorticoids like cortisol can inhibit glucose uptake in skeletal muscle and can lead to fat gain, obesity, insulin resistance, hypertension, dyslipidemia and type-2 diabetes. Cortisol, which is produced in your adrenal glands in response to stress is good in small quantities and at the right time. However, long term elevated levels can have serious health implications, as mentioned earlier. Emodin can stop elevated cortisol levels right at the source. Emodin is a selective inhibitor of 11β-HSD1 only, not 11β-HSD2 which is found in your kidneys. Inhibiting this enzyme can cause major health effects such as sodium/potassium absorption/elimination, buildup of excess mineralocorticoids, interfere with aldosterone and affect kidney function.

Emodin inhibits 11β-HSD1 by blocking the enzyme site from sending a hydride from NADP to cortisone to produce cortisol. Studies show emodin inhibits the enzyme by up to 46% in adipose tissue(fat cells) which means your body is producing almost half of the cortisol it normally would. This can lead to fat loss, reduction in stress, decreased insulin resistance and increased insulin sensitivity. Emodin also reduced fasting blood glucose levels by 77% after taken orally for 7 days, as well as overall plasma insulin levels by 66% relative to the control. In another study, emodin was shown to reduce appetite and bodyweight in mice(13.9% reduction in bodyweight).

As you can see, emodin is a very powerful ingredient for inhibiting cortisol and insulin-induced weight gain. Unfortunately, the oral bioavailability is very low. In order to fix this issue, we added a large dose of piperine, commonly known as black pepper extract. In a study combining emodin with piperine showed a marked increase in bioavailability via inhibiting glucuronidation. This is the process where a glucose molecule is attached to emodin to make it more water soluble and easy to expel from the body. By stopping this process, the piperine allows emodin to maximally be absorbed and inhibit the formation of cortisol and help you meet and exceed your weight loss goals. This product can be taken by both men and women and works especially well for high-intensity athletes and fitness competitors.

______________________________________________________

Feng, Ying, et al. "Emodin, a natural product, selectively inhibits 11β‐hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet‐induced obese mice." British journal of pharmacology 161.1 (2010): 113- 126. Di, Xin, Xin Wang, and Youping Liu. "Effect of piperine on the bioavailability and pharmacokinetics of emodin in rats." Journal of pharmaceutical and biomedical analysis 115 (2015): 144-149. Wang, Yue-jing, et al. "Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice." Acta Pharmacologica Sinica 33.9 (2012): 1195.



Read The Studies On The Ingredients Below

https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1476-5381.2010.00826.x
https://www.nature.com/articles/aps201287#introduction


Shipping
Unfortunately we do not ship outside of the United States 
Delivery

Estimated between  and

Will usually ship within 1 business day.

   

Please allow 3-5 days for your order to arrive. All orders are processed and shipped within 24-48 hours unless otherwise noted.

Returns are easy, simply contact us for a returns number and send your item to our returns centre for fast processing. Please note we can only accept unopened items for return or refund.

Here are more great reasons to buy from us:

In the unlikely event that you find your item cheaper at another online store, just let us know and we'll beat the competitor's pricing hands-down.

We insist that you love everything you buy from us. If you're unhappy for any reason whatsoever, just let us know and we'll bend over backwards to make things right again.

Ordering from Shoptimized is 100% safe and secure so you can rest easy. Your personal details are never shared, sold or rented to anyone either.

Chemix - Cortibloc

$54.99

Don't Take Our Word For it! Here's What Our Customers Think:

Added to cart!
Anti-Hero Labs - Carnage
Someone recently purchased a 10 minutes ago
Anti-Hero Labs - Venom
Someone recently purchased a 12 minutes ago
Axxcelerated Sports Nutrition - Mammoth Resurrection
Someone recently purchased a 5 minutes ago
Axxcelerated Sports Nutrition - Reaper Resurrection
Someone recently purchased a 2 minutes ago
Axxcelerated Sports Nutrition - Sasquatch Resurrection
Someone recently purchased a 3 minutes ago
Axxcelerated Sports Nutrition - Yetti Resurrection
Someone recently purchased a 10 minutes ago
BioLabs - Freaky Hard
Someone recently purchased a 13 minutes ago
BioLabs - Mass King 60 tabs
Someone recently purchased a 3 minutes ago
BioLabs - OX XXL Mass Builder
Someone recently purchased a 7 minutes ago
Black Label Nutrition - Cycle Aid
Someone recently purchased a 12 minutes ago
Black Label Nutrition - Essential PCT *Out Of Stock
Someone recently purchased a 18 minutes ago
Black Label Nutrition - Pheni-Chill
Someone recently purchased a 15 minutes ago
Black Label Nutrition - Str8 Burn
Someone recently purchased a 12 minutes ago
Black Label Nutrition - Str8 Fire
Someone recently purchased a 5 minutes ago
Black Label Nutrition - Testrol
Someone recently purchased a 15 minutes ago
Black Label Nutrition - Tranquil
Someone recently purchased a 18 minutes ago
Black Label Nutrition - Tudca
Someone recently purchased a 2 minutes ago
Black Magic Supply - Brain Waves
Someone recently purchased a 5 minutes ago
Black Magic Supply - BZRK High Potency Pre-Workout
Someone recently purchased a 6 minutes ago
Black Magic Supply - Dry Spell
Someone recently purchased a 9 minutes ago

.. people are viewing this item

Only .. left! .. people are viewing this, and .. recently purchased it

   
Free Shipping on All Orders Over $50! Free shipping when you order over XX You Have Qualified for Free Shipping Spend $x to Unlock Free Shipping You Have Achieved Free Shipping Free Shipping For Over $x to Free Shipping on Orders Over $50 You Have Achieved Free Shipping Free shipping when you order over $1000 ou Have Qualified for Free Shipping